Emeritus Professor Richard Clayton

简介

Richard Clayton has a first degree in Applied Physics and Electronics from the University of Durham, and a PhD in Medical Physics from the University of Newcastle upon Tyne. After completing his PhD, Richard continued research at the Freeman Hospital in Newcastle upon Tyne, funded by British Heart Foundation junior and intermediate fellowships.The main focus of these projects was on understanding the electrical mechanisms that underlie life-threatening disorders of heart rhythm, based on the analysis of data recorded from patients. A move to the University of Leeds, funded by a British Heart Foundation Lectureship enabled Richard to work on developing mechanistic models of cardiac electrophysiology in the human heart.Richard Clayton was appointed Senior Lecturer in the School of Computer S

代表成果

• Frost F, Balmus M, Bokeria L, Longbottom J, Rangel-Smith C, Saxton H, Clayton RH, Niederer S, Rothman AMK, Worden K & Wilkinson RD (2026) Rapid personalisation of cardiovascular models using invasively measured right ventricular pressure. Computers in Biology and Medicine, 213, 111811-111811.
• Lim Z, Chauhan RA, Roper-Jones B, Allen E, Mitcheson J, Clayton RH, Brack KE & Ng GA (2026) Role of beta-adrenergic modulation of action potential duration in arrhythmogenesis in Long QT Syndrome Type 1 & 2. Autonomic Neuroscience, 265, 103427-103427.
• Mamajiwala M, Corrado C, Lanyon CW, Niederer SA, Wilkinson RD & Clayton RH (2026) Rapid calibration of atrial electrophysiology models using Gaussian process emulators in the ensemble Kalman filter.. Sci Rep.
• Preston SP, Wilkinson RD, Clayton RH, Chappell MJ & Mirams GR (2025) Think before you fit: parameter identifiability, sensitivity and uncertaintyin systems biology models. Current Opinion in Systems Biology, 100563-100563.
• Saxton H, Taylor DJ, Faulkner G, Halliday I, Newman T, Schenkel T, Morris PD, Clayton RH & Xu X (2025) The impact of experimental designs & system sloppiness on the personalisation process: A cardiovascular perspective. PLoS One, 20(6). View this article in WRRO
• Tonko JB, Sattler S, Dalgas Nissen S, Jerltorp K, Seshan S, Chow A, Jespersen T, Clayton R & Lambiase P (2025) Differentiating mechanisms of long duration ventricular fibrillation in acute ischemic myocardium vs. chronic infarct in an in-vivo porcine model. EP Europace, 27(Supplement_1). View this article in WRRO
• Sridhar S & Clayton RH (2025) The effect of non-local coupling of fibroblasts on pacing dynamics in a 2D tissue: a simulation study. Scientific Reports, 15(1). View this article in WRRO
• Holland BL, Monk NAM, Clayton RH & Osborne CP (2025) Implementing a framework of carbon and nitrogen feedback responses into a plant resource allocation model. in silico Plants, 7(1). View this article in WRRO
• Weiner OJF, Das M, Clayton RH, McComb JM, Murray A, Parry G & Lord SW (2025) Sympathetic reinnervation in cardiac transplant recipients: Prevalence, time course and association with long-term survival. The Journal of Heart and Lung Transplantation, 44(2), 204-212. View this article in WRRO
• Mamalakis M, Banerjee A, Ray S, Wilkie C, Clayton RH, Swift AJ, Panoutsos G & Vorselaars B (2024) Deep multi-metric training: the need of multi-metric curve evaluation to avoid weak learning. Neural Computing and Applications, 36(30), 18841-18862. View this article in WRRO