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AB
Education
- D.Phil. University of Minnesota, Twin Cities, 2005
- Professor of Computer Science
- Professor of Biochemistry
- Associate Professor in the Department of Electrical and Computer Engineering
- Faculty Network Member of the Duke Institute for Brain Sciences
Selected publications
- He L, Bartesaghi A. prismPYP: Power-spectrum and image domain learning for self-supervised micrograph evaluation. Structure (London, Englandu202f: 1993). 2026 Jun;34(6):988-999.e4.
- Liu H-F, Zhou Y, Huang Q, Martin J, Bartesaghi A. In situ structure determination of conformationally flexible targets using nextPYP. Nature protocols. 2026 Feb;21(2):851u201371.
- Bartesaghi A. Strategies for studying discrete heterogeneity in situ using cryo-electron tomography. Current opinion in structural biology. 2025 Dec;95:103186.
- Sokratian A, Zhou Y, Tatli M, Burbidge KJ, Xu E, Viverette E, et al. Mouse u03b1-synuclein fibrils are structurally and functionally distinct from human fibrils associated with Lewy body diseases. Sci Adv. 2024 Nov;10(44):eadq3539.
- Huang Q, Zhou Y, Bartesaghi A. MiLoPYP: self-supervised molecular pattern mining and particle localization in situ. Nature methods. 2024 Oct;21(10):1863u201372.
- Washington EJ, Zhou Y, Hsu AL, Petrovich M, Tenor JL, Toffaletti DL, et al. Structures of trehalose-6-phosphate synthase, Tps1, from the fungal pathogen Cryptococcus neoformans: A target for antifungals. Proc Natl Acad Sci U S A. 2024 Aug 6;121(32):e2314087121.
- Watson AJI, Bartesaghi A. Advances in cryo-ET data processing: meeting the demands of visual proteomics. Current opinion in structural biology. 2024 Aug;87:102861.
- Washington EJ, Zhou Y, Hsu AL, Petrovich M, Tenor JL, Toffaletti DL, et al. Structures of trehalose-6-phosphate synthase, Tps1, from the fungal pathogen Cryptococcus neoformans : a target for novel antifungals. 2024.
- Huang Q, Zhou Y, Liu H-F, Bartesaghi A. Joint micrograph denoising and protein localization in cryo-electron microscopy. Biological imaging. 2024 Jan;4:e4.
- Sokratian A, Zhou Y, Tatli M, Burbidge K, Xu E, Viverette E, et al. Mouse u03b1-synuclein fibrils are structurally and functionally distinct from human fibrils associated with Lewy body diseases. bioRxiv. 2024.
Data verified 9/6/2026Source