Gizem Buldum

About

I’m a Lecturer at the School of Computing at Newcastle University and a member of the Interdisciplinary Computing and Complex Biosystems (ICOS) group. My research focuses on Engineering Biology, integrating synthetic biology, laboratory automation and bioprocess development to design, build, and optimise biological systems. I received my PhD from Imperial College London, where I also held postdoctoral positions subsequently. Prior to joining Newcastle University, I worked in the biopharmaceutical industry. I led upstream bioprocess development teams and supported the translation of lab-scale innovations into manufacturing processes. My work brings together expertise from engineering, biotechnology and computation to address challenges in biological design and manufacturing. In my team, we

Education

• PhD, Imperial College London

Selected publications

• ro-crate-rs: Development of a Lightweight RO-Crate Rust Library for Automated Synthetic Biology
• Evolutionary Landscapes of Amylases and Their Carbohydrate Binding Modules
• The automated Galaxy-SynBioCAD pipeline for synthetic biology design and engineering
• Systematic Understanding of Recent Developments in Bacterial Cellulose Biosynthesis at Genetic, Bioprocess and Product Levels
• Design, Development and Optimization of a Functional Mammalian Cell-Free Protein Synthesis Platform
• Cell-free protein synthesis using Chinese hamster ovary cells
• Linking synthetic genetic circuit kinetic modeling to cellulose biosynthesis prediction in Escherichia coli: towards bioprocessing of microbial cell factories
• Recombinant biosynthesis of bacterial cellulose in genetically modified Escherichia coli
• Investigation of the in vivo interaction between β-lactamase and its inhibitor protein
• More Than Meets the Eye in Bacterial Cellulose: Biosynthesis; Bioprocessing; and Applications in Advanced Fiber Composites